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-   -   New Strain of Staph infection (http://www.soulforce.org/forums/showthread.php?t=4400)

keltic63 01-16-2008 08:06 AM

New Strain of Staph infection
 
http://www.npr.org/templates/story/s...oryId=18086925


Quote:

Health officials are tracking a new type of infection with Staphylococcus aureus that is resistant to even more antibiotics than MRSA, the drug-resistant staph that has spread from coast to coast over the past seven years. (MRSA stands for "methicillin-resistant Staphylococcus aureus".)
So far, nearly all recognized cases of the multiply drug resistant staph have been among gay and bisexual men. The cases are showing up most often in San Francisco, Los Angeles and New York.

Have any of you heard about this news item? I first learned of this yesterday and have been pondering over it now for the past 24 hours. this may be an opportunity for those who are against us to renew their battle, much like the response to AIDS in the 80's.

I'm also concerned for the health and safety of all our members here at soulforce. Please be careful, be picky about whom you choose to be intimate with, and by all means, be safe. Advice from the medical community seems to be that washing thoroughly with soap and water is a good defense against these MRSA type staph infections.

andrewlittle 01-16-2008 08:24 AM

Interestingly, since I check medical news a lot, this is the first time I have heard about this disease with specific links to gay people. There have been little stories here and there, but none that seem to reflect the seriousness with which this infection should be treated.

Since it passed by skin-to-skin contact, it can be very contagious. One has to wonder why it is has been linked to gay men specifically, when that kind of contact is hardly exclusive to them.

Right or wrong, all kinds of warning bells went off in my head when I read it. Is the link real, or imagined? Does it show assumptions? Since we don't know, the best course of action is, of course, care. The story I read said the greatest number of cases was from the Castro district, which could indicate that was the entry point, and infection of gay men being a logical conclusion based on community demograhics.

It is rife for political and religious manipulation, that's for sure.

Zerbie 01-16-2008 09:15 AM

I've been hearing some about staph aureus, but the MRSA kind, with specific reference to the elderly and those infected in hospitals, but not a "new" kind of staph aureus. Neither have I heard it linked to gay men - I agree with Andy's assessment: linking staph to gay men in particular seems suspect to me, above all b/c it's illogical based on the casual and easy way it transmits.

BenL 01-16-2008 11:55 AM

This is the article I read yesterday. It was posted on GLEE.com. It caught my eye because Boston was mentioned.

http://www.sfgate.com/cgi-bin/articl...E0L8.DTL&tsp=1

antonyh 01-16-2008 07:31 PM

HRC Response
 
As anticipated, the Religious Right are having a field day with this. Here is HRC's response:

Quote:

Originally Posted by HRC
President Joe Solmonese issued the following statement in response to CWA’s lies and distortions:

"We’ve come to expect hysteria and gross distortions from an organization like this and normally their bigoted rants don’t even warrant a response. But the statement today about MRSA is beyond the pale. In typical fashion, they disregard the facts and instead chose to demagogue the issue in order to fear-monger. Serious medical issues deserve serious consideration, not wildly off-the-mark press releases from anti-gay groups trying to capture media attention.

We saw this kind of hysteria in the early 1980’s around HIV/AIDS, I’ll be damned if we will sit idly by in 2008 and let them perpetrate that type of anti-gay hysteria without calling them out on it."

http://www.hrc.org/8624.htm


ladyinred 01-16-2008 09:17 PM

I have to agree with Zerbie and Andy The story seems to be suspicious, my mother had a serious staph infection and the hospital docs said staph is contagious no matter what, even in hospitals people are not immune to staph infections. I also read where staph is everywhere, some immune systems are more prone to get it I guess particular ones that are weakened. My ex has a mother who is a nurse and ,she goes to the doctor for everything, she has more illness than I do and I don't even use anti-bacterial soap. She's had the flu shot, goes to the dermatologist, has diabetes, arthritis among other things. She is now living with her mother who is big on the anti-germ thing, and is meticulously clean and they still get sick alot. I figure we are surrounded by germs...LOL Can't avoid all of them. As far as facts by organizations affilated with the right, I wouldn't trust 'em as far as I'd throw them. They see gay people as diseased anyway.

Daniel 01-16-2008 09:20 PM

This is the article I read a few days ago...
 
http://www.nytimes.com/2008/01/15/he...on&oref=slogin

Quote:

January 15, 2008
New Bacteria Strain Is Striking Gay Men

By LAWRENCE K. ALTMAN
A new, highly drug-resistant strain of the “flesh-eating” MRSA bacteria is being spread among gay men in San Francisco and Boston, researchers reported on Monday.

In a study published online by the journal Annals of Internal Medicine, the bacteria seemed to be spread most easily through anal intercourse but also through casual skin-to-skin contact and touching contaminated surfaces.

The authors warned that unless microbiology laboratories were able to identify the strain and doctors prescribed the proper antibiotic therapy, the infection could soon spread among other groups and become a wider threat.

The new strain seems to have “spread rapidly” in gay populations in San Francisco and Boston, the researchers wrote, and “has the potential for rapid, nationwide dissemination” among gay men.

The study was based on a review of medical records from outpatient clinics in San Francisco and Boston and nine medical centers in San Francisco.

The Castro district in San Francisco has the highest number of gay residents in the country, according to the University of California, San Francisco. One in 588 residents is infected with the new multidrug-resistant MRSA strain, the study found. That compares with 1 in 3,800 people in San Francisco, according to statistical analyses based on ZIP codes.

A separate part of the study found that gay men in San Francisco were about 13 times more likely to be infected than other people in the city.

The San Francisco researchers suggested that scrubbing with soap and water might be the most effective way to stop skin-to-skin transmission, particularly after sexual activities.

MRSA, for methicillin-resistant Staphylococcus aureus, was once spread chiefly in hospitals. But in recent years, a number of healthy people have acquired it outside hospitals.

Nearly 19,000 people died in the United States from MRSA infections in 2005, the Centers for Disease Control and Prevention has reported.

The infection can cause unusually severe problems, including abscesses and skin ulcers. The bacteria can invade through the skin to produce necrotizing fasciitis, giving them the popular name of flesh-eating bacteria. They can also cause pneumonia, damage the heart and produce widespread infection through the blood.

Among gay men in the study, MRSA was spread by skin contact, causing abscesses and infection in the buttocks and genital area.

The new strain is closely related to earlier ones. Both are known as MRSA USA300.

The strain is much more difficult to treat because it is resistant not just to methicillin, but also many more of the antibiotics used to treat the earlier strains, said Dr. Henry F. Chambers, an author of the new study.

The new strain contains a plasmid called pUSA03.

“This particular clone is resistant to at least three other drugs, clindamycin, tetracycline and mupirocin,” Dr. Chambers said in a telephone interview.

Of the alternatives recommended by the C.D.C. and the Infectious Diseases Society of America, trimethoprim-sulfamethoxazole (Bactrim), clindamycin and a tetracycline, “this strain is resistant to two of those three,” he added. “In addition, the new strain is resistant to mupirocin, which has been advocated for eradicating the strain from carriers.”
And here is the link the medical journal source.

http://www.annals.org/cgi/content/fu...802190-00204v1

Some key information from the article.

Quote:

Results: The overall incidence of multidrug-resistant USA300 infection in San Francisco was 26 cases per 100 000 persons (95% CI, 16 to 36 cases per 100 000 persons); the incidence was higher in 8 contiguous ZIP codes with a higher proportion of male same-sex couples. Male–male sex was a risk factor for multidrug-resistant USA300 infection (relative risk, 13.2 [CI, 1.7 to 101.6]; P < 0.001) independent of past MRSA infection (relative risk, 2.1 [CI, 1.2 to 3.7]; P = 0.007) or clindamycin use (relative risk, 2.1 [1.2 to 3.6]; P = 0.007). The risk seemed to be independent of HIV infection. In San Francisco, multidrug-resistant USA300 manifested most often as infection of the buttocks, genitals, or perineum. In Boston, multidrug-resistant USA300 was recovered exclusively from men who have sex with men.

Limitations: The study was retrospective, and sexual risk behavior was not assessed.

Conclusions: Infection with multidrug-resistant USA300 MRSA is common among men who have sex with men, and multidrug-resistant MRSA infection might be sexually transmitted in this population. Further research is needed to determine whether existing efforts to control epidemics of other sexually transmitted infections can control spread of community-associated multidrug-resistant MRSA.
And the Editor's Note- regarding the article- is interesting.

Quote:

Editors' Notes

Context: Researchers have recently identified multidrug-resistant USA300, a clone of community-acquired, methicillin-resistant Staphylococcus aureus (MRSA) that is resistant to multiple antibiotics.

Contributions: These authors demonstrate that the incidence of multidrug-resistant USA300 MRSA is highest in the areas of San Francisco where more male same-sex couples reside. The infection frequently manifests as an abscess or cellulitis in the buttocks, genitals, or perineum, and male–male sex was a risk factor.

Cautions: The data were passively reported or retrospectively collected and are therefore subject to bias.

Implication: Multidrug-resistant USA300 MRSA infection is especially common among men who have sex with men. It might be sexually transmitted in this population.
Passively reported? I guess this means who these incidences were reported too, how is was reported, and what was done with with the information- all after the fact. Subject to what? Exaggeration? Anti-gay bias? Error?

Still- it seems that there are gay men with a serious infection which is drug resistant. Gotta know who you are sleeping with folks. Remember the mantra in the 80's and 90's? Medically speaking- you are sleeping with everyone the person you are sleeping with has slept with.

Another thing that I think is important here.

USE A CONDOM!

This is what I believe the editor's correctly put there finger on when they noted that "sexual risk behavior was not assessed".

ladyinred 01-16-2008 09:23 PM

Ok here is some info I found off the website:http://www.cdc.gov/ncidod/dhqp/ar_mrsa_ca_public.html

What is MRSA (methicillin-resistant Staphylococcus aureus)?
Some staph bacteria are resistant to antibiotics. MRSA is a type of staph that is resistant to antibiotics called beta-lactams. Beta-lactam antibiotics include methicillin and other more common antibiotics such as oxacillin, penicillin and amoxicillin. While 25% to 30% of the population is colonized with staph, approximately 1% is colonized with MRSA.

Who gets staph or MRSA infections?
Staph infections, including MRSA, occur most frequently among persons in hospitals and healthcare facilities (such as nursing homes and dialysis centers) who have weakened immune systems. These healthcare-associated staph infections include surgical wound infections, urinary tract infections, bloodstream infections, and pneumonia.

What is community-associated MRSA (CA-MRSA)?
Staph and MRSA can also cause illness in persons outside of hospitals and healthcare facilities. MRSA infections that are acquired by persons who have not been recently (within the past year) hospitalized or had a medical procedure (such as dialysis, surgery, catheters) are know as CA-MRSA infections. Staph or MRSA infections in the community are usually manifested as skin infections, such as pimples and boils, and occur in otherwise healthy people.

How common are staph and MRSA infections?
Staph bacteria are one of the most common causes of skin infection in the United States and are a common cause of pneumonia, surgical wound infections, and bloodstream infections. The majority of MRSA infections occur among patients in hospitals or other healthcare settings; however, it is becoming more common in the community setting. Data from a prospective study in 2003, suggests that 12% of clinical MRSA infections are community-associated, but this varies by geographic region and population.


What does a staph or MRSA infection look like?
Staph bacteria, including MRSA, can cause skin infections that may look like a pimple or boil and can be red, swollen, painful, or have pus or other drainage. More serious infections may cause pneumonia, bloodstream infections, or surgical wound infections.

Are certain people at increased risk for community-associated staph or MRSA infections?
CDC has investigated clusters of CA-MRSA skin infections among athletes, military recruits, children, Pacific Islanders, Alaskan Natives, Native Americans, men who have sex with men, and prisoners.
Factors that have been associated with the spread of MRSA skin infections include: close skin-to-skin contact, openings in the skin such as cuts or abrasions, contaminated items and surfaces, crowded living conditions, and poor hygiene.
Also this website:http://www.mayoclinic.com/health/mrsa/DS00735
MRSA infection

ARTICLE SECTIONS
Introduction
Signs and symptoms
Causes
Risk factors
When to seek medical advice
Screening and diagnosis
Treatment
Prevention


Introduction
Methicillin-resistant Staphylococcus aureus (MRSA) infection is caused by Staphylococcus aureus bacteria — often called "staph." Decades ago, a strain of staph emerged in hospitals that was resistant to the broad-spectrum antibiotics commonly used to treat it. Dubbed methicillin-resistant Staphylococcus aureus (MRSA), it was one of the first germs to outwit all but the most powerful drugs. MRSA infection can be fatal.

Staph bacteria are normally found on the skin or in the nose of about one-third of the population. If you have staph on your skin or in your nose but aren't sick, you are said to be "colonized" but not infected with MRSA. Healthy people can be colonized with MRSA and have no ill effects. However, they can pass the germ to others.

Staph bacteria are generally harmless unless they enter the body through a cut or other wound, and even then they often cause only minor skin problems in healthy people. But in older adults and people who are ill or have weakened immune systems, ordinary staph infections can cause serious illness.

In the 1990s, a type of MRSA began showing up in the wider community. Today, that form of staph, known as community-associated MRSA, or CA-MRSA, is responsible for many serious skin and soft tissue infections and for a serious form of pneumonia.



Nov 9, 2007
© 1998-2008 Mayo Foundation for Medical Education and Research (MFMER). .
DS00735
Also these websites;http://www.cdc.gov/ncidod/dhqp/ar_mr...illanceFS.html

http://www.vdh.virginia.gov/Epidemio...eillance/MRSA/

http://www.newstarget.com/z020027.html

http://tahilla.typepad.com/mrsawatch...rsa/index.html

http://www.bionewsonline.com/c/2_wha...roorganism.htm

MRSA USA300.Voyich et al. “Is Panton-Valentine Leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease?” J Infect Dis 2006;194:1761-70.

Labandeira-Rey et al. examine the virulence of USA 300 strains of MRSA and show that Panton-Valentine leukocidin (PVL) causes lung necrosis and death with nasal challenge in mice. BUT Voyich et al. tested the same hypothesis using intramuscular and intravenous challenge, and concluded that PVL is nothing more than a marker for the USA 300 strain. The truth may be someplace in the middle. http://www.journals.uchicago.edu/doi...10.1086/509506


Note :USA300 is also known as ca mrsa.

Now this will expose alot:http://findarticles.com/p/articles/m...3/ai_n19449387
excerpted from this article:
Quote:

Until recently, methicillin-resistant Staphylococcus aureus (MRSA) has caused predominantly healthcare-associated infections. We studied MRSA infections and overall skin and soft tissue infections (SSTIs) in outpatients receiving care at the Baltimore Veterans Affairs Medical Center Emergency Care Service during 2001-2005. We found an increase in MRSA infections, from 0.2 to 5.9 per 1,000 visits (p<0.01); most were community-associated SSTIs. Molecular typing showed that >80% of MRSA infections were caused by USA300. In addition, SSTI visits increased from 20 to 61 per 1,000 visits (p<0.01). The proportion of SSTI cultures that yielded MRSA increased from 4% to 42% (p<0.01), while the proportion that yielded methicillin-sensitive S. aureus remained the same (10% to 13%, p = 0.5). The increase in community-associated MRSA infections and the overall increase in SSTIs in our population suggest that USA300 is becoming more virulent and has a greater to cause SSTIs.......The population for our retrospective study was derived from the Veterans Affairs Maryland Health Care System (VAMHCS), which provides comprehensive health care to >45,000 veterans in the Maryland area. Outpatient care is provided at 2 medical centers and 3 community-based outpatient clinics. Our ECS is located in the Baltimore VA Medical Center and serves [approximately equal to] 85 patients a day.
Also:We reviewed microbiology cultures obtained during an ECS visit from October 1, 2000, through September 30, 2005 (fiscal years [FYs] 2001-2005), in which MRSA was first isolated from a patient's culture. The total number of ECS visits per FY was obtained from administrative records. The MRSA infection risk was calculated by dividing the total number of ECS patients whose culture results were MRSA positive for the first time by the number of ECS visits per FY. Information about patient demographics, clinical manifestations, and risk factors for nosocomial acquisition of MRSA was obtained from manual review of the VA's computerized patient record system.


AHA !!!!


Nothing disgusts me more than the right twisting facts and information to demonize gay people.Anyone who wants to use this information to post on their website or to document it or for other purposes, please feel free to do so.
Quote:

So far, nearly all recognized cases of the multiply drug resistant staph have been among gay and bisexual men. The cases are showing up most often in San Francisco, Los Angeles and New York.
Yeah right.

Quote:

Health officials are tracking a new type of infection with Staphylococcus aureus that is resistant to even more antibiotics than MRSA
Yeah right. Apparently it isn't so new. BS Equals the ridiculous right. Here is some more info:
http://boards.crimelibrary.com/showthread.php?t=287685

http://www.add-articles.com/Article/...ut-MRSA/142726

http://www.zonegrippeaviaire.com/showthread.php?p=5345

http://tahilla.typepad.com/mrsawatch...rsa/index.html

http://findarticles.com/p/articles/m.../ai_n13609417: April, 2005 ,outbreak of community-associated methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infection (SSTI) occurred in a college football team from August to September 2003. Eleven case-players were identified, and boils were the most common sign. Linemen had the highest attack rate (18%). Among 99 (93% of team) players with cultured specimens, 8 (8%) had positive MRSA nasal cultures. All available case-players' MRSA isolates characterized had the community-associated pulsed-field type USA300. A case-control study found that sharing bars of soap and having preexisting cuts or abrasions were associated with infection.(Only sexually transmitted by homosexual men?)

http://www.pamshouseblend.com/showDiary.do?diaryId=4170

keltic63 01-16-2008 10:27 PM

folks, I've been doing some research, as I see many of you have, and I've arrived at the same conclusions that you have: the study is suspicious. HOWEVER, that has not stopped certain organizations from taking the bait and running with it. Concerned Women for America has already started the gay-bashing. Right wing, fundamentalist news sources are already using this particular study with its sensationalist numbers concerning the infection in San Francisco to condemn gay men. Run for your DeLoreans, folks, we're headed back to the 1980's!

I just posted on my blog about this.....click on my signature below (this terrestrial ball) and feel free to comment liberally on this!

ladyinred 01-16-2008 10:29 PM

More information
 
Yeah right a gay disease.
http://www.omega-international.com.au/multidrug.html




--------------------------------------------------------------------------------

This important Special Report of the Bio/Tech News deals with an old and yet, in many
ways, new product which might very well have a major role to play in the coming
onslaught of these - and numbers of other - disease causing, MDR ("Multi-Drug
Resistant") Microbes. That product is "Colloidal Silver". Be sure you read what
follows very carefully. There is a real possibility that the information contained
herein could end up saving your life or that of a loved one. At the very minimum,
your health and well-being could turn out to be vastly improved and strengthened.

As always, permission is hereby granted for our subscribers to pass copies of this
newsletter on to family members, friends and business associates, provided that you
copy it in its entirety without omission or alteration of any kind and that you give
it to them without charge.

Finally, we want to be clear about this; what follows is for informational purposes only.
It is not an attempt by the writers or publisher of the Bio/Tech News to practice
medicine nor should it be construed to be such. Readers are hereby encouraged to
consult with a trusted and competent medical professional concerning the content of
this newsletter and any recommendations contained herein.

The Advent of "Andromeda Strains"

"The time has come to close the book on infections diseases."
Surgeon General of the United States (Testimony before Congress, 1969)

To reiterate some of what was said in the Editor's Note above, the 1940's ushered in
the age of exciting new "miracle drugs", beginning with penicillin. At the time
these drugs were considered the most important medical discovery in the battle
against infectious diseases. With the introduction of antibiotic-based
chemotherapy, the conquest of infectious disease seemed complete. "The
perception in the 1960's was that we had conquered almost every infectious disease,"
says Dr. Thomas Beam of the Buffalo New York VA Medical Center. Unfortunately,
during the next decade that victory began to unravel. Today we know that medicine's
purported triumph over infectious diseases has become an illusion. As Sharon
Begley of Newsweek Magazine suggests, "It looks like medicine declared victory and
went home too soon".


--------------------------------------------------------------------------------


Disease-causing bacteria are becoming alarmingly resistant to antibiotics.

In an address before the American Association for the advancement of Science on
February 19th, 1994, Dr. Alexander Tomasz voiced the concern of scientists, clinical
microbiologists, medical practitioners and public health professionals about the rapid
rise of antibiotic-resistant bacteria. It seems that bacteria have bested the "miracle
drugs" we've been relying on for our medical security.

Some of the more threatening Multi-drug resistant (MDR) "Bugs" which have begun to
gain a foothold are MDR Staphylococcus aureus, MDR Enterococcus faecium and MDR
Tuberculosis (See the Bio/Tech News alarming Special Report, "TB Alert ! ", which
focuses on the prospects of the "white plague" returning upon us with a
vengeance).

The first penicillin-resistant Pneumococcus was discovered two years before the
above-quoted statement by the U.S. Surgeon General. It was found in Papua New
Guinea. By 1977, an epidemic disease caused by Pneumococcus was being reported
by South African hospitals. The bug had not only become resistant to penicillin but
other antibiotics as well, and an increase in its level of resistance by more than
several thousand fold was reported. Since the early 1990's MDR Pneumococcus has
demonstrated its ability to spread from one country to another, reaching extremely
high levels in some countries.

Pneumococcus is the culprit behind outbreaks of pneumonia in various communities
worldwide. This bacterium is a major threat to public safety because it can be life
threatening to certain ill or elderly patients (40,000-50,000 Americans die from
exposure to Pneumococcus each year; there's no telling what will happen if MDR
Pneumococcus should gain a foothold - Ed.) It also causes life-threatening infections
of the bloodstream, and meningitis.

Pneumococcus is responsible for nearly half of the visits to pediatricians each year. It
is the major "causative agents" of middle ear infections in children. According to
Tomasz, young children under age 2 are at high risk of acquiring diseases caused by
Pneumococcus. He says "several day-care centers in the U.S. were shown to have
particularly high frequency of carriage of MDR pneumococcal strains". The bugs have
spread through day-care centers "like a chain letter", says one reporter.

Staphylococcus aureus is the most common cause of skin, wound and bloodstream
infection in hospitalized patients. A number of strains of this pathogen here in the U.S.
and elsewhere have now become resistant to almost all available antibiotics. In most
hospitals, the only remaining line of defence against the spread of MDR Staph aureus
in an antibiotic by the name of Vancomycin. How long it will hold is anybody's guess.

Enterococcus faecium has already acquired resistance to Vancomycin. In 1992 it had
become the third most frequent "causative agent" of hospital-acquired wound and
urinary tract infections, septicemia, and endocarditis. As of this writing, some strains
of this bacterium are not killed by any available antibiotic agents. Tomasz regretfully
admits, "If you get the infection, you are in the Almighty's hands."

(Imagine being a physician having to face a situation in which your patient has gone
into the hospital for elective surgery and contracts an infection "caused" by some bug
floating around in the hospital and for which there is no known antibiotic cure!

The alert reader will no doubt have noticed that we place "causative agent" and
"cause" in quotes (see above), the reason being that the terms are a capitulation of
sorts to the "germ theory" of disease, an outdated, simplistic medical model which will
one day have to give way to other, more accurate medical paradigms which have
been developing despite pressures to maintain the status quo. We intend to keep our
subscribers posted on the progress of these exciting changes - Ed.)

Infectious disease specialists points to patients, doctors and drug companies for for
contributing to the problem by promoting indiscriminate and excessive use of drug
antibiotics. Without realizing it, they have all given the bugs new life. Patients often
demand - and doctors often irresponsibly comply - an antibiotic for illnesses like the
common cold and various viral infections which do not respond to antibiotics. (They
don't respond because they are viral. Antibiotics are specific to bacteria and, in some
cases, fungi, not viruses. Doctors know this and therefore act irresponsibly either
when they prescribe antibiotics for viral problems or prescribe antibiotics prematurely
(not knowing if the symptoms presented are due to bacteria or viruses), "just in case"
and/or just to give the patient the impression that they are "going something" for
them. Ed.) Each dose taken of an antibiotic makes it easier for resistance to spread.

Another cause of resistance is the flood of antibiotics which have entered the food
chain. Farm animals receive 30 times more antibiotics than people do. These remain
in the animal's flesh, which we then eat. And milk contains up to 80 different
antibiotics; with every glassful people swallow minute amounts of these drugs. The
result: in a recent study at Rutgers University, antibiotics at levels deemed "safe" for
human consumption by the FDA were shown to have increased the rate at which
resistant bacteria are emerging by 600 to 2700 percent.

The antibiotic problem has grown to a crisis level largely because the drugs have been
used so widely. This has set into motion a microscopic-level struggle from which have
emerged "super" microbes. Scientists believe that these actually develop a mutant
gene of resistance to the drug. The mutants then pass on their resistant genes to their
progeny. On bacterium can leave 17,777,220 offspring within 24 hours. The more an
antibiotic is used, the greater the chances that it will kill off the weaker microbes but
leave these mutated germs to reproduce. Eventually, these new version entirely
replace the original strains, and the original antibiotic is no longer effective.

All this explains the new sense of anxiety sweeping the medical community as
scientists stand by and watch while one illness-causing microbe after another wins its
battle against antibiotics. Once considered the ultimate "miracle-drugs", antibiotics are
now being overcome by bacteria which have managed, by sheer force of numbers,
ways to beat them.

The April 1994 editorial in the New England Journal of Medicine called for urgent
action, including surveillance for early signs of drug resistance and more disciplined
use of antibiotics. Some specialists are now willing to admit that, as infections become
harder to successfully treat with drugs, our only real alternative may be more natural
methods.


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Dark Clouds.......Silver Lining?

Since 1938, silver has been standing in the wings, waiting to make a big comeback.
Not for it's monetary value, but for properties inherent in it that make it worth more
than its weight in gold: silver is a unique healing agent.

Once known worldwide as a powerful antiseptic in its best medical form, in the 1940's
use of silver was dropped in favour of newly-discovered antibiotics. As a result,
colloidal silver has turned out to be the remedy that modern medicine almost forgot.
Yet it seems we need silver now more than ever as out once highly-vaunted "miracle drugs" rapidly fail to live up to earlier expectations. No known disease-causing organism can live in the presence of even minute traces of the chemical element of metallic silver. (This includes destructive bacteria, viruses and fungi which, when compared with antibiotics, is one of the things which makes silver unique, antibiotics are specific to bacteria and, in some cases, fungi, but never viruses - Ed.) From his bacteriological experiments with silver Dr. Henry Crooks has concluded, "I know of no microbe that is not killed in laboratory experiments in six minutes." And, while antibiotics are quickly losing their effectiveness as several strains or immunity to silver. (This is another unique property of silver - Ed.) To top it off, silver is virtually non-toxic, making it safe for both children and adults - and even their pets. (Again, a property unique to silver - Ed.)


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History of Silver Usage

From ancient times men have used silver as healing agent. Silver has long been known as an antiseptic with the power to kill bacteria and other germs. Ancient Greeks and Romans kept their liquids free of contamination by placing them in silver jars. The indigenous people of India and the Orient have known about the tremendous healing quantities of silver for centuries. It's still common practice for people in the east to wrap some if their food in paper-thin pieces of silver - and eat it! During the early 1900's a silver foil was still considered the best infection-preventative dressing for a wound.

American settlers travelling across the West often put a silver dollar in their milk to delay spoilage. Silver goblets have long been used in religious ceremonies because the silver is known to act as antiseptic , the silver keeps the wine fresh and lessons the possibility of the transmission of germs as the goblet is passed from person to person. Until recently silver has been a stable utensil on the dining table. People cooked on silver pans and then ate from silver plates and with silver knives and forks. Some modern researchers have speculated that by using silver, our parents and grandparents were ingesting particles of silver which aided in their immunity to many diseases.


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Medicinal Uses of Silver

Medicinal uses of silver through history have included the use of silver foil and plates to replace missing bone fragments. Silver nitrate has long been prescribed for stomach ulcers. Silver drops are still placed in newborn babies' eyes to kill bacteria which cause blindness. Silver has been used as cure for herpes. A silver-based ointment has been found effective against syphilis, cholera and malaria. It is still applied to certain eye, nose and throat infections.

Around the turn of the century scientists had demonstrated that silver processed a certain way could function as a main-stay of antibiotic treatment. Known as "colloidal silver", it was quite "high tech" for its time, but compared with today's silver colloids, it was technically inferior. The Colloid Research Foundation reports, "one of the main drawbacks in the production method of the 1900's was the technology used. The silver particle size never reached its optimum ultra-microscopic size to get the most out of silver."

"Colloid" refers to a substance that consists of ultra-fine particles that do not dissolve but remain suspended in a medium of a different matter.The particles in a true colloid normally ranges in size from about 0.01 to 0.001 of a micron in diameter. Although these particles are larger than most molecules, they are still invisible to the naked eye. (To get a feel for the scale, imagine a human red blood cell to be about the size of a silver dollar, coccus bacteria would then range from about the size of a button on a man's dress shirt on down to the diameter of a BB; and, a particle of colloidal silver would be about the size of the period at the end of one of these sentences - Ed).

Although there have been a number of different techniques developed in an attempt to achieve a true silver colloid, the best and most effective method is the electrical process since it is the only method which preserves the necessary homogeneity, minuteness of granules, purity and stability to create a true colloid (Examples of other methods which have been employed are mechanical grind, ultrasonic and chemical - Ed.) A true colloid of silver is composed of particles of ultrafine, 99.999% silver, electrically charged and held in suspension in a solution of de-ionized water. According to the Colloid Research Foundation, the highest quality colloidal silver consists of the maximum number of particles of the minimum possible size with the ultimate solution having a huge number of particles of one atom, each carrying an electrical charge. A true silver colloid should not contain any artificial stabilizers of chemical additives of any kind (which are present in some silver products presently on the market; som e even going so far as to use an artificial yellow dye in order to give proper golden yellow colour of the true silver colloid - Ed.)

Prior to 1933, colloidal silver was administered in just about every way that modern drugs are administered today. It was injected both intravenously and intramuscularly, used as a gargle for throat conditions, applied as a douche, taken orally and applied topically even for sensitive tissues, and dropped into the eyes. And this great healing power of silver is no secret to world-class scientists today. "Silver is the best all around germ-fighter we have," says Dr. Harry Margraf of St. Louis. Dr. Richard L. Davies, executive director of the Silver Institute which monitors silver technology in 37 countries concurs: "In four years, we've described 87 important new medical uses for silver. We're just beginning to see to what extent silver can relieve suffering and save lives."

The comeback of silver in medicine began in the 1970's when Dr. Carl Moyer, chairman of Washington University's Departments of Surgery received a grant to develop a better treatment for burn victims. Chief biochemist Dr. Margraf worked with Moyer and others to find an antiseptic strong yet safe enough to use over large areas of the body. They reviewed 22 antiseptic compounds before trying silver. Today silver is being used in seventy percent of the burn centers in the U.S. This story, reported in an article in Science Digest in 1978, demonstrates the profound healing power of silver:

"A speeding car overturned and burst into flames. The 18 year old driver suffered burns all over his face, neck, arms, hands, back, stomach, and legs, - burns covered more than 80 percent of his body. Until recently, this would have been a death sentence. Doctors knew how to restore vital body fluids and salts, but had no way to fight infection, the primary cause of death in burn cases. Fortunately for this youth, a new silver compound killed deadly bacteria and enabled him to heal. He was out of the hospital within four months".


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--------------------------------------------------------------------------------


Antiseptic and Preventive Uses of Silver

In the former Soviet Union silver is used to sterilize recycled water aboard space shuttles. NASA has also selected a silver/water system for its space shuttle. Internationally, many airlines use silver water filters to guarantee passenger safety against water-borne diseases such as dysentery. The Swiss government has approved use of such silver water filters in homes and offices. Here in the U.S., some city municipalities use silver in the treatment of sewerage. Silver works so well in purifying water that it is sometimes used to purify swimming pool water, and it doesn't sting the eyes as chlorine does. An experiment conducted in Nebraska demonstrates its effectiveness; fifty gallons of sewerage were pumped into a pool without any disinfectant. A standard measure of contamination is the count of E.coli, an organism found in the intestinal tract. The count soared to 7000 E.coli cells per milliliter of water. When the water was exposed to silver electrodes, within three hours it was completely free of E.coli.

Japanese firms have developed at least five technologies which use silver to purify the air. Silver is now the latest agent in the fight against airborne toxins and other industrial poisons in the Japanese work place.


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ladyinred 01-16-2008 10:31 PM

http://dev.smm.org/buzz/blog/staph_superbug_alert
Staph Superbug alert
by mdr on Oct. 18th, 2007
in Life Science, Biological Populations Change Over Time, and Human Organism 14



Staphylococcus aureus: Public domain image courtesy Wikimedia.There’s a new Superbug scare going on in the United States. The Staph Superbug is an evolved strain of staphylococcus aureus that is super-resistant to several common antibiotics. Called MRSA (for Methicillin-Resistant Staphylococcus Aureus), its most recent victims are an 11-year-old Mississippi girl, and a 17-year-old Virginia student whose death resulted in the entire school district closing down. That was by no means an overreaction. Infections have been reported in four other states, and residents are becoming concerned. And no wonder. US officials warn that the Staph Superbug could infect 90,000 people this year in the United States. In 2005, more than 18,500 people died from it.

In the past, most MRSA infections were contracted mainly in hospitals or health care facilities, but what's got officials worried is that the infection is now showing up more in community-based locations such as daycare centers, prisons, and schools.

Many people carry Staph on their person without even knowing it. The bacteria can live in the nose or on the skin of healthy individuals without affecting them adversely. It's passed from one person to another by contact, and becomes a problem when it gets inside your body, through a cut or open sore. Usually, traditional antibiotics such as penicillin can defend against the germ. But in recent years, over-prescribing of antibiotics coupled with the bacteria’s ability to quickly evolve a resistance against those antibiotics has produced the current deadly strain of the bug.

Health officials say the best defense against Staph is good basic hygiene, such as washing your hands often, and not sharing personal items. JGordon wrote extensively about this in a previous post.

Symptoms of Staph infection can vary and depend on where the infection is located. Externally, it can show up as boils in the skin (furuncle) or as a red, warm and painful localized skin infection (cellulites), or cause blisters or honey-colored crusted skin lesions (impetigo), or infection of hair follicles (folliculitis). It's most dangerous when it infects the blood stream because then it can be transported anywhere in your body. These are but a few of the possible symptoms.

If you do get infected with MRSA, early treatment is critical. Two drugs that can defend against the Superbug are Vancomicin and Vactrum, but only if it’s caught in its early stages.

LINKS AND MORE INFO

Post Chronicle story
Fox News story
Staph infection info
Antibiotics Resistance
More about MRSA
More on Staph infection symptoms

Email this page Tags : public health, bacteria, epidemic, staphylococcus aureus, health, infectious Also:
https://secure.willamette.edu/dspace...ology_2007.pdf

http://www.bionewsonline.com/c/2_wha...roorganism.htm

antonyh 01-16-2008 10:35 PM

Great work finding that study Daniel.

Gregory_de_Bois 01-16-2008 10:41 PM

Quote:

The risk seemed to be independent of HIV infection.
So that means that it wasn't related to HIV-AIDS? I am pretty skeptical of these studies, I mean how could a stapph infection be exclusively with gays?

Daniel 01-16-2008 10:48 PM

Quote:

Originally Posted by Gregory_de_Bois (Post 50238)
So that means that it wasn't related to HIV-AIDS? I am pretty skeptical of these studies, I mean how could a stapph infection be exclusively with gays?

I think it means that the infection was not limited to those with HIV.

I'm not saying I know squat, but here's one hypothesis to what's going on: gay man leaves hospital with staph infection and has sex at local bathhouse. Same thing could happen to a straight person ie a sex club, btw.

Interesting thing is that the study doesn't give the reader an actual count of how many folks were infected. Or didn't I read it right? It gives a percentage of the population.

What do you guys think?

I find this curious.

ladyinred 01-16-2008 10:59 PM

Daniel what about this?After reading this what is your conclusion about the research?
A reader writes:

Interesting that you mentioned the MRSA article from Annals of Internal Medicine, but I'm surprised that you didn't note the limitations of this study. The Annals editors wrote in their summary

“The data were passively reported or retrospectively collected and are therefore subject to bias.”
They went on:

"Our study has limitations...
Our incidence estimates for San Francisco come from a passive surveillance system and may underestimate the incidence of true infection. We relied on retrospective chart review for identification of risk factors for multidrug-resistant USA300 infection in the 2 clinic populations; because data were not collected or documented systematically, our estimates of risk may be influenced by selection, referral, documentation, or other biases. Specific sexual behaviors were not assessed or documented in clinic charts; we therefore cannot comment on the association between multidrug-resistant USA300 infection and specific male–male sexual practices."
MRSA has been around a long time, and as a practicing Navy physician I have seen outbreaks in millitary populations for years. A 2005 study by the Navy Environmental Health Center that did not make any headlines showed that community acquired MRSA was present in 3-5 % of Navy recruits. There have been significant outbreaks in the SEAL training school in San Diego, as well as the Marine Recruit Training Depot, but this has not made the news. MRSA has also been a problem for years in hospitals and nursing homes. Now that someone has found a community outbreak in a gay population, it's "big" news ... bullshit.
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Daniel 01-16-2008 11:09 PM

Quote:

Originally Posted by ladyinred (Post 50242)
Daniel what about this?After reading this what is your conclusion about the research?

I think we will find out that we're talking about bathhouse sex. And that the what is being reported is being overblown.

Something of the sort happened here in NYC (with regards to AIDS) this past summer. There was a lot of hoopla with the health comissioner going nuts and a mini media circus. It all turned out to be a total exaggeration.

We shouldn't forget that getting one's study into a journal affects one's payraise at work. ;)

I've be tuning into the Gay USA on our own local Public Access channel tomorrow night to get the lowdown on this. If anyone will know the scoop, it will be Andy Humm and Ann Northrop.

http://homepage.mac.com/depeche7/GayUSA/Personal13.html

ladyinred 01-16-2008 11:15 PM

I also found this article:
 
From science direct:Clinical Microbiology Newsletter
Community-associated methicillin-resistant Staphylococcus aureus: It's not just in communities anymore

Fred C. Tenover Ph.D. (D) A.B.M.M., , Associate Director for Laboratory Science
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention (G08), Atlanta, Georgia

Available online 18 February 2006.



Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) infections continue to spread worldwide. From an epidemiologic perspective, the risk factors for infections caused by health care-associated strains of methicillin-resistant S. aureus (HA-MRSA) include hospitalization within the last year; having had surgery, received dialysis, or resided in a long-term care facility in the previous year; having a permanent indwelling catheter or percutaneous medical device; or having previously had an MRSA infection. Strains causing infections in patients without risk factors for MRSA are called community-associated MRSA (CA-MRSA). The laboratory definition of CA-MRSA is more of a moving target. While CA-MRSA strands typically are resistant only to oxacillin and macrolides, carry SCCmec type IV, and harbor the genes encoding the Panton-Valentine leukocidin toxin, there are at least four distinct lineages defined by pulsed-field gel electrophoresis that fit this definition. CA-MRSA strains are already moving into a variety of health care institutions and causing infections. Thus, the line between HA- and CA-MRSA is blurring.


Mailing Address: Fred C. Tenover, Ph.D. (D) A.B.M.M., Associate Director for Laboratory Science, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention (G08), 1600 Clifton Rd., Atlanta, GA 30333. Tel.: 404-639-3375. Fax: 404-639-3288
Here is :http://www.journals.uchicago.edu/doi/pdf/10.1086/509856

and:http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5609a3.htm

http://www.nursingcenter.com/prodev/...p?CE_ID=746060

Here is what I typed in for my findings: multidrug-resistant USA300 infection it's origination and causes This seems to me another scare tactic linking homosexuality with this particular infection.. Who knows now they'll probably say Gay men need to be quaranteened now. I also want to get to the bottom of this as well. I will also look foward to Daniel's findings as well as others. But one thing I cannot stand is a distortion of information when it is used for the right's purpose to further stigmatize gays and lesbians and to oppress them. Why don't lesbians get this if it is confined to homosexuality?Suspicious, yes..... This seems of be indicative to people who have immune systems who are seriously compromised. can we always trust what is reported in the media? Probably not, I tend to gather information from other sources or independent news sources and medical and other scientific studies.

keltic63 01-16-2008 11:25 PM

here's the thing that is bothering me about all this: this particular strain of MDR-MRSA was known about in 2003, yet this particular report from California, touts this as a "new" strain, and puts the blame squarely on the gay community. I'm having trouble believing that the report is unbiased, or that it is merely reporting the "numbers". My hunch is (and I recognize the need to follow these more closely) that this particular report is either politically motivated (funded perhaps, by an organization with a a conservative agenda) or, as Daniel has pointed out, motivated by greed: getting published means getting a raise; getting published with a lot of media publicity/controversy gets even more attention, and perhaps a better raise.

the footnote to all of this: NPR reports that an 81 year old woman in NYC has the MDR-MRSA (USA-300) infection.

ladyinred 01-16-2008 11:39 PM

Originating in homosexual and bisexual men?
 
Introduction
Staphylococcus aureus was first documented as a human pathogen in the 19th century. Today, it is a frequently isolated pathogen causing serious, invasive infections such as soft tissue infections, endocarditis, osteomyelitis, bacteremia, septic arthritis, and nosocomial pneumonia. Available treatment options for serious invasive disease due to S. aureus are limited because of increasing antimicrobial resistance. Of particular concern is the increasing frequency of methicillin-resistant S. aureus (MRSA), especially in the United States. Recent surveys of S. aureus isolates report MRSA rates in the United States as high as 50%.[1, 2] The rates of MRSA are higher in patients in the intensive care unit and in those with nosocomial infections (often > 60%).[2–4] In addition to the increased rates of methicillin resistance isolated from hospitalized patients, recent reports cite concern regarding the growing frequency of MRSA acquired in the community setting, known as community-onset or community-acquired MRSA (CA-MRSA).[5, 6] Clinical, microbiologic, and economic outcomes associated with invasive S. aureus infections are less than optimal[7] and generally worse for patients with infections caused by MRSA.[8–10]

Vancomycin is considered by many to be the mainstay for the treatment of invasive infections caused by multidrug-resistant S. aureus, in part because of extensive published experience in the treatment of serious, invasive infections and a favorable safety profile.[11] However, vancomycin treatment outcomes in serious infections other than skin and skin structure infections (such as nosocomial pneumonia, endocarditis, and meningitis) are less than optimal.[11, 12] For example, vancomycin cure rates were reported to be 35.5% in a subset of patients with nosocomial pneumonia due to MRSA who participated in a randomized trial.[13] More recently, patients with MRSA endocarditis or bacteremia who participated in a randomized trial and were treated with vancomycin had a clinical success rate of only 31.8%.[14] Several drug-related factors may contribute to such poor outcomes. Vancomycin's microbiologic activity may be compromised in the presence of biofilms produced by some S. aureus organisms.[15, 16] In addition, investigators evaluating S. aureus isolates from patients receiving long-term vancomycin therapy for bacteremia concluded that loss of an accessory gene-regulator function in MRSA contributed to treatment failure.[15] Bacterial eradication rates for vancomycin may also be related to a ratio of drug exposure (characterized as area under the concentration-time curve [AUC]) to minimum inhibitory concentration (MIC).[17] Therefore, vancomycin's failure to reach sufficient concentrations in selected tissues and fluids (such as lung tissue) could also contribute to poor outcomes.[18, 19]

Despite maintaining 100% susceptibility in vitro (based on published interpretive breakpoint standards) against S. aureus in numerous surveillance studies,[11, 20, 21] there is growing concern regarding escalating MICs of staphylococci to vancomycin.[12, 15, 22] Case reports have been published of infections due to S. aureus with intermediate in vitro susceptibility to vancomycin (VISA), with MICs of either 4 or 8 µg/ml.[23–29] In addition, there are reports of S. aureus with MICs of 1–4 µg/ml that, when subjected to stepwise passage through increasing concentrations of vancomycin, yield subpopulations with increased MICs to vancomycin (usually at least 8 µg/ml).[30–33] Such resistance in S. aureus has been termed "heteroresistant" (h-VISA). Finally, isolated case reports in the United States of patients with infections due to vancomycin-resistant S. aureus (VRSA)[34, 35] underscore the need to identify new treatment alternatives.

Patients with multidrug-resistant S. aureus infections intolerant to or failing vancomycin therapy previously have had limited treatment options. Newer therapies (e.g., linezolid, quinupristin-dalfopristin, daptomycin, and tigecycline) are available, but they need to be compared with other agents that have favorable in vitro activity against S. aureus ( Table 1 ).

Section 1 of 8Next Page: Older Antibacterials for Resistant Staphylococcus aureus Infections This type of infection has been also documented in Canada and other countries.

ladyinred 01-16-2008 11:45 PM

Politically motivated? By religious conservatives who call themselves Christians, hardly Christ-like I'd say. Thou shalt not bear false witness and lie? Do they have any moral standards such as valueing truthfulness and objectivity? Forgive my dogged determination to search for the truth but slander and untruthfulness or distorting information to support an agenda or ones biases doesn't sit well with me.Especially when it is used maliciously to hurt people.Lies are spread all over the internet all the time and people will tend to believe the information unless they take time to read between the lines and do a little research on their own.The fact is sexually transmitted diseases have been around for centuries and are not confined to one particular group. Sexually transmitted disease is common throught out the world:http://www.euro.who.int/document/e79822.pdf

Why lies like this hurt people is because it assumes mainly that homosexual men seem to get this through sexual contact, while not including other facts about this particular type of infection, that infants,school children can get it ,athletes through casual contact, nursing homes, this does a diservice to the public by not relaying truthful and factual information. People need factual and truthful information so they can take precautions, both the gay and straight community.The right can again be called irresponsible for omitting certain facts and as usual their cause is destructive, not for the welfare or benefit of our communities.That may indeed sound harsh but look at the facts. If they only want to distort and twist the truth to further their agenda to oppress gays, they can hardly be called honest.

If they had presented the information with integrity it would be different.While they may have had had a valid point that this is a problem with gay men, had they had pointed out other information with a balanced view it would be different. Even the gay community points out certain problems in the gay community but this can be done without the intent to demonize or oppress gay people even more. The problem the right has is they tend to alienate and demonize the people they don't like or agree with, they want consideration for their views but often attack people who don't agree with theirs, liberals are Godless, devils, gay are the anti-Christ, women who have abortions are murderers, and the list goes on.

They act as if persecuted and as if their rights are being attacked when in fact they enjoy many priveleges that many citizens don't have.They act as if they own the country and the keys to heaven. I personally think they can't be too happy when they are so judgmental of others.Or when they level meaness and intolerance at those they don't understand or even want to understand. Their ideology to me cannot make sense or serve any constructive end..Their theology is rife with violence, not only animosity aimed at others who don't agree with their world view, but vengefulness and cruelty and meaness.


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