The charities that touch my heart are veterans' organizations (especially disabled veterans - my stepfather was a vet), animal protection (except for PETA, although I agree with some of their views), wildlife habitat and restoration (especially birds), and of course anything benefiting children and the elderly. So I guess you could lump that into animals, children and the elderly! Soft spots in my heart for all of them. I also have Soulforce and Human Rights Campaign on my list of donations. And cannot leave out various family and friends that need help.
Even if I'm unable to give money or lunches or clothes, often a genuine smile with eye contact, a handshake, some kind words will mean more than money - and the least we can do is the most - send some prayers up.