Yes, negative thoughts can cause depressed moods. But we cannot oversimplify. Depression also causes negative thoughts.
The best approach to a clinical depression is to tackle the medical angle in cooperation with your doctors (you get a say in treatment, too, that is critically important), and then immediately begin training the mind to think positively as a habit. But the chemicals themselves can keep you thinking negative thoughts just as surely as a brick wall can keep you from walking through it.
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Never linger too long with the ignorant,
throw stones at their talk.
Walk only with the lovers,
the mirror of the soul gets rusty when
dipped in muddy water.
-Rumi
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